Strategic Modulation of Caspase Signaling: Z-VDVAD-FMK as...

2025-10-18

This article explores the mechanistic and translational significance of Z-VDVAD-FMK, an irreversible caspase-2 inhibitor, in apoptosis and cell death research. Integrating foundational caspase biology, recent insights into cell death modalities from cancer studies, and practical strategies for experimental design, we chart a path for leveraging Z-VDVAD-FMK in high-impact disease modeling and therapeutic innovation.